A Rational Drug Combination Design Proves to Inhibit Epithelial-Mesenchymal Transition in a Three-Dimensional Microenvironment

نویسندگان

  • Farnaz Barneh
  • Mehdi Mirzaie
  • Payman Nickchi
  • Mehran Piran
  • Mona Salimi
  • Fatemeh Goshadrou
  • Amir Reza Aref
  • Mohieddin Jafari
چکیده

1 Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2 Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. 3 Department of Applied Mathematics, Faculty of Mathematical Sciences, Tarbiat Modares University, Tehran, Iran. 4 Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada. 5 Department of Physiology and Pharmacology, Pasteur Institute of Iran, Tehran, Iran. 6 Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, USA.

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تاریخ انتشار 2017